Date: 2019
Type: Article
Cognitive reappraisal and expressive suppression of negative emotion in combat-related posttraumatic stress disorder : a functional MRI study
Cognitive therapy and research, 2019, Vol. 43, No. 1, (SI), pp. 236-246
BUTLER, Oisin, WILLMUND, Gerd, GLEICH, Tobias, ZIMMERMANN, Peter, LINDENBERGER, Ulman, GALLINAT, Juergen, KUEHN, Simone, Cognitive reappraisal and expressive suppression of negative emotion in combat-related posttraumatic stress disorder : a functional MRI study, Cognitive therapy and research, 2019, Vol. 43, No. 1, (SI), pp. 236-246
- https://hdl.handle.net/1814/66015
Retrieved from Cadmus, EUI Research Repository
Difficulties in the regulation of emotion are hypothesized to play a key role in the development and maintenance of posttraumatic stress disorder (PTSD). The current study used functional magnetic resonance imaging (fMRI) to assess neural activity during task preparation and image presentation during different emotion regulation strategies, cognitive reappraisal and expressive suppression, in PTSD. Patients with combat-related PTSD (n=18) and combat-exposed controls (n=27) were instructed to feel, reappraise or suppress their emotional response prior to viewing combat-related images during fMRI, while also providing arousal ratings. In the reappraise condition, patients showed lower medial prefrontal neural activity during task preparation and higher prefrontal neural activity during image presentation, compared with controls. No difference in neural activity was observed between the groups during the feel or suppress conditions, although patients rated images as more arousing than controls across all three conditions. By distinguishing between preparation and active regulation, and between reappraisal and suppression, the current findings reveal greater complexity regarding the dynamics of emotion regulation in PTSD and have implications for our understanding of the etiology and treatment of PTSD.
Additional information:
Published: 16 March 2018
Cadmus permanent link: https://hdl.handle.net/1814/66015
Full-text via DOI: 10.1007/s10608-018-9905-x
ISSN: 0147-5916; 1573-2819
Publisher: Springer
Grant number: H2020/677804/EU
Sponsorship and Funder information:
Military Medical Academy of German Armed Forces, German Ministry of Defense International Max Planck Research School on the Life Course (LIFE) German Federal Ministry of Education and ResearchFederal Ministry of Education & Research (BMBF) German Science FoundationGerman Research Foundation (DFG) AstraZenecaAstraZeneca LundbeckLundbeck Corporation Janssen-CilagJohnson & Johnson USAJanssen Biotech Inc LillyEli Lilly OtsukaOtsuka Pharmaceutical German Science Foundation (DFG)German Research Foundation (DFG) [KU 3322/1-1, SFB 936/C7] European UnionEuropean Union (EU) [ERC2016-StG-Self-Control]
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